Immunology – bio402 (3 credits)
This course examines the key concepts of immunology. Topics include the development and anatomy of the immune system, innate immunity, the structure and function of immunoglobulin, cellular interactions, disease, and histocompatibility.
Immunoglobulin and B Cells
- Explain the basic structure of an immunoglobulin.
- Differentiate among the different isotypes.
- Summarize the biology of B lymphocytes from origin to surface molecules.
Major Histocompatibility Complex (MHC)
- Determine the structure of MHC class I and class II molecules and their interactions with other cell types.
- Analyze the interaction between genetic variability of MHC and transplantation.
Hypersensitivity and Immunodeficiency
- Compare type II, type III, and type IV hypersensitivity.
- Describe the development and progression of allergic reactions.
- Analyze the progression of HIV infection to the development of AIDS as a model of immunodeficiency disorders.
- Relate causes and effects of neoplasms of the immune system.
- Summarize the biology of T lymphocytes from origin to surface molecules.
- Analyze the reactions of T and B lymphocytes with each other as well as with other cell types.
- Explain the importance of cytokines and their receptors in immune responses.
Development and Anatomy of the Immune System
- Compare innate and acquired immunity.
- Differentiate between humoral and cellular immunity.
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